SCHEMBL12410753

SCHEMBL12410753

CN(C)c1ncnc2c1ncn2C(C)(C)C

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.60
PI4K2B Q8TCG2 2/20 0.60
PI4K2A Q9BTU6 2/20 0.60
PI4KB Q9UBF8 2/20 0.60
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14356547 0.77 PI4KA (0.66) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL9604572 0.77 CYP1A2 (0.69) CYP1A2CYP2D6MAPK1
SCHEMBL9705702 0.75 CYP1A2 (0.62) CYP1A2CYP2D6MAPK1
SCHEMBL10248598 0.75 PI4KA (0.64) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL21126195 0.75 PI4KA (0.64) PI4KAPI4K2BPI4K2API4KB
SCHEMBL4569753 0.75 PI4KA (0.64) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL5021593 0.75 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KB
SCHEMBL8466944 0.74 CYP1A2 (0.49) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL12194505 0.72 PI4KA (0.60) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL10149296 0.72 PI4KA (0.60) PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773132-B2 Cyclic di-nucleotides as stimulator of interferon genes modulators BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2023-10-03 US disclosed
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF RIKEN GENESIS CO., LTD. (JP) 2023-08-17 US disclosed
US-20200331957-A1 CYCLIC DI-NUCLEOTIDES AS STIMULATOR OF INTERFERON GENES MODULATORS AJ SCIENCES (YIXING) CO., LTD (CN) 2020-10-22 US disclosed
US-20130289013-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SUNOVION PHARMACEUTICALS INC. 2013-10-31 US disclosed
US-8497278-B2 Imidazo[1,2-a]pyridine compounds SUNOVION PHARMACEUTICALS INC. (US) 2013-07-30 US disclosed
US-20110166146-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SUNOVION PHARMACEUTICALS INC. (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166146-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS PAICS, ITPA, DPYD PI4KA 924/4885PI4K2B 1442/4885PI4K2A 854/4885
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF NSUN2, NSUN3, POLRMT PI4KA 3910/4885PI4K2B 4406/4885PI4K2A 4334/4885
US-20130289013-A1 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS PAICS, ITPA, DPYD PI4KA 924/4885PI4K2B 1442/4885PI4K2A 854/4885
US-20200331957-A1 CYCLIC DI-NUCLEOTIDES AS STIMULATOR OF INTERFERON GENES MODULATORS STING1, IRF3, CGAS PI4KA 2615/4885PI4K2B 2369/4885PI4K2A 2302/4885
US-11773132-B2 Cyclic di-nucleotides as stimulator of interferon genes modulators STING1, IRF3, CGAS PI4KA 2615/4885PI4K2B 2369/4885PI4K2A 2302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.