SCHEMBL12412467

SCHEMBL12412467

Cc1ccc(N=Nc2ccc3ccccc3c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 11/20 0.66
RAB9A P51151 11/20 0.66
MEN1 O00255 9/20 0.66
KMT2A Q03164 9/20 0.66
HSP90AA1 P07900 3/20 0.66
TDP1 Q9NUW8 5/20 0.58
CYP2A6 P11509 2/20 0.58
L3MBTL1 Q9Y468 5/20 0.54
GAA P10253 1/20 0.53
HTR3E A5X5Y0 2/20 0.47
HTR3B O95264 2/20 0.47
HTR3A P46098 2/20 0.47
HTR3D Q70Z44 2/20 0.47
HTR3C Q8WXA8 2/20 0.47
MAPT P10636 5/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
MAPK1 P28482 3/20 0.47
POLB P06746 3/20 0.45
KDM4E B2RXH2 2/20 0.45
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926700 0.87 CYP1A2 (0.59) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL3283287 0.87 MEN1 (0.75) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL10017620 0.87 MEN1 (0.75) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL2291265 0.85 MEN1 (0.73) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL10349716 0.85 MEN1 (0.73) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL24354410 0.82 CYP1A2 (0.65) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL14280920 0.79 RAB9A (0.66) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL12412502 0.79 RAB9A (0.66) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL29153271 0.79 MEN1 (0.66) NPC1RAB9AMEN1KMT2AHSP90AA1
SCHEMBL11891993 0.79 RAB9A (0.66) NPC1RAB9AMEN1KMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 US disclosed
US-20110052885-A1 WATER SOLUBLE AZO COMPOUND OR SALT THEREOF, INK COMPOSITION AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed
US-7771525-B2 Water-soluble azo compound or salt thereof, ink composition and colored product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-08-10 US disclosed
US-20100068475-A1 WATER-SOLUBLE AZO COMPOUND OR SALT THEREOF, INK COMPOSITION AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-03-18 US disclosed