Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | CAMK1D | Q8IU85 | 12/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412568 | 0.90 | PTPN11 (0.40) | HRH4CAMK1DACACBHRH3 | |
| SCHEMBL21624806 | 0.84 | CAMK1D (0.45) | CAMK1DMKNK1MKNK2 | |
| SCHEMBL21624807 | 0.84 | CAMK1D (0.45) | CAMK1DMKNK1MKNK2 | |
| SCHEMBL950844 | 0.78 | GRM2 (0.43) | HRH4HRH3MKNK1MKNK2AKT1 | |
| SCHEMBL16872992 | 0.78 | MKNK1 (0.43) | HRH4MKNK1MKNK2DYRK1A | |
| SCHEMBL16872993 | 0.78 | MKNK1 (0.43) | HRH4MKNK1MKNK2DYRK1A | |
| SCHEMBL950845 | 0.78 | GRM2 (0.43) | HRH4HRH3MKNK1MKNK2AKT1 | |
| SCHEMBL12503204 | 0.77 | HRH4 (0.47) | HRH4HRH3MKNK1MKNK2AKT1 | |
| Hydrochloric Acid SCHEMBL955771 | 0.77 | GRM2 (0.42) | HRH4HRH3MKNK1MKNK2AKT1 | |
| SCHEMBL12412537 | 0.77 | ACACB (0.42) | ACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | TOP2B, TOP1, POLI | HRH4 3053/4885CAMK1D 458/4885ACACB 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.