SCHEMBL12414864

SCHEMBL12414864

CCCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CCC)c4ccc(Br)cc4C3(C)C)=C2Cl)C(C)(C)c2cc(Br)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.56
PRMT5 O14744 2/20 0.56
PRMT8 Q9NR22 2/20 0.56
CARM1 Q86X55 1/20 0.56
PTPN1 P18031 1/20 0.39
APP P05067 1/20 0.33
FOLH1 Q04609 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
S1PR2 O95136 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
ALPG P10696 1/20 0.32
THRB P10828 1/20 0.32
PKM P14618 1/20 0.32
XBP1 P17861 1/20 0.32
CRHBP P24387 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12414892 0.96 PRMT1 (0.55) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414865 0.92 PRMT1 (0.67) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL26684573 0.92 PRMT1 (0.53) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414857 0.92 PRMT1 (0.61) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL26684783 0.91 PRMT1 (0.45) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414866 0.91 PRMT1 (0.45) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL25357251 0.88 PRMT1 (0.66) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL30390320 0.88 PRMT1 (0.66) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414894 0.88 PRMT1 (0.66) PRMT1PRMT5PRMT8CARM1PTPN1
Iodide SCHEMBL30976567 0.88 PRMT1 (0.67) PRMT1PRMT5PRMT8CARM1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230384671-A1 LAMINATE OF NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
EP-4269122-A1 LAMINATE OF NEGATIVE LITHOGRAPHIC PRINTING PLATE ORIGINAL PLATE AND METHOD FOR MANUFACTURING NEGATIVE LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2023-11-01 EP disclosed
US-20110165518-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-07-07 US disclosed