Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 9/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.67 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.67 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | FOLR1 | P15328 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28946990 | 1.00 | PRMT1 (0.67) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL30390320 | 0.99 | PRMT1 (0.66) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12414894 | 0.99 | PRMT1 (0.66) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL25357251 | 0.99 | PRMT1 (0.66) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12414865 | 0.95 | PRMT1 (0.67) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL25863685 | 0.94 | PRMT1 (0.59) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12414857 | 0.92 | PRMT1 (0.61) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12414892 | 0.92 | PRMT1 (0.55) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12832513 | 0.92 | PRMT1 (0.56) | PRMT1PRMT5CARM1PRMT8PTPN1 | |
| SCHEMBL12414895 | 0.90 | PRMT1 (0.54) | PRMT1PRMT5CARM1PRMT8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107699-A2 | CYANINE-BASED FLUOROPHORES | THE GENERAL HOSPITAL CORPORATION (US) | 2024-05-23 | — | — | WO | disclosed |