SCHEMBL12414940

SCHEMBL12414940

CCCCCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CCCCC)c4ccc(I)cc4C3(C)C)=C2Sc2ccccc2)C(C)(C)c2cc(I)ccc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 8/20 0.46
HTR1A P08908 1/20 0.45
PRMT5 O14744 2/20 0.45
PRMT8 Q9NR22 2/20 0.45
CARM1 Q86X55 1/20 0.45
PTPN1 P18031 1/20 0.42
FOLR1 P15328 5/20 0.40
FOLH1 Q04609 4/20 0.39
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12414943 0.91 HTR1A (0.52) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414856 0.88 PRMT1 (0.41) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414937 0.87 PTPN1 (0.52) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414855 0.86 PRMT1 (0.50) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414942 0.86 PRMT1 (0.45) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414949 0.85 PRMT1 (0.52) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414930 0.85 FOLR1 (0.41) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL14597399 0.84 HTR1A (0.57) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL13955050 0.84 PRMT1 (0.51) PRMT1HTR1APRMT5PRMT8CARM1
SCHEMBL12414953 0.84 PTPN1 (0.50) PRMT1HTR1APRMT5PRMT8CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110165518-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-07-07 US disclosed