SCHEMBL12415274

SCHEMBL12415274

Cc1cc(CCC(=O)OCCS)cc(C)c1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.43
APP P05067 2/20 0.43
ALOX5 P09917 1/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
CYP4Z1 Q86W10 1/20 0.37
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
P2RY12 Q9H244 1/20 0.36
KMT2A Q03164 1/20 0.35
NLRP3 Q96P20 1/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352297 0.89 ALOX5 (0.47) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL12386503 0.85 ALOX5 (0.49) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL13412641 0.83 CYP4F2 (0.59) TDP1ALDH1A1CYP4F2CYP4A11CYP4Z1
SCHEMBL10312309 0.82 TDP1 (0.41) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL12415241 0.81 CYP4F2 (0.49) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL10920115 0.81 GAA (0.46) TDP1ALDH1A1APPALOX5KMT2A
SCHEMBL14570406 0.80 ALOX5 (0.45) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL6071507 0.80 ALOX5 (0.52) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL19047012 0.77 ALOX5 (0.57) TDP1ALDH1A1APPALOX5CYP4F2
SCHEMBL12919720 0.77 CYP4F2 (0.44) TDP1ALDH1A1APPALOX5CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110163284-A1 LIGHTING UNIT COVER FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110155976-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
US-20100130638-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2010-05-27 US disclosed