Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.87 |
| ▸ | NOS2 | P35228 | 5/20 | 0.56 |
| ▸ | NOS1 | P29475 | 4/20 | 0.56 |
| ▸ | NOS3 | P29474 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ARG2 | P78540 | 4/20 | 0.53 |
| ▸ | ARG1 | P05089 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL29126333 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL30642401 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL30642405 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL29397119 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL28422142 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL9070593 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL7131633 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL2400402 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL2400405 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL30647269 | 1.00 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3164 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250311761-A1 | METHOD FOR THE PREPARATION OF A NUTRITIONAL POWDER | NESTLE SA (CH) | 2025-10-09 | — | — | US | claimed |
| US-12427129-B2 | Application of compound amino acids in preparation of medicament for improving sensitivity of bacteria to antibiotics | SUN YAT-SEN UNIVERSITY (CN) | 2025-09-30 | — | — | US | claimed |
| CN-119949497-A | Formula powder containing multiple amino acids and preparation method thereof | 山东美吉客生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119925389-A | Compound amino acid and glucose injection and preparation method thereof | 湖北一半天制药有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119924295-A | Cell preservation solution and application thereof | 深圳华大基因细胞科技有限责任公司 | 2025-05-06 | — | — | CN | claimed |
| EP-4539683-A1 | POWDERED FOOD COMPOSITION FOR THE PREPARATION OF DRINKS FOR THE HYDRATION OF DYSPHAGIC INDIVIDUALS | General Beverage S.r.l. (IT) | 2025-04-23 | — | — | EP | claimed |
| CN-119837793-A | Anticreep antipruritic composition and preparation method and application thereof | 珠海安肽生物医药技术开发有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119818484-A | 14-Amino acid and glucose composition stored in double-chamber bag and preparation method thereof | 湖北一半天制药有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119751921-A | Preparation method of amide bond crosslinked sodium hyaluronate hydrogel | 浙江景嘉医疗科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119707769-A | Method for preparing caprolactam by using fermentation liquor containing lysine, lysine or lysine salt as raw materials | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| EP-1161956-A1 | MEDICINAL COMPOSITIONS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | claimed |
| WO-2001051026-A2 | INSTANT GRANULES AND PROCESS FOR THEIR FORMULATION | DR. GERGELY & CO. (AT) | 2001-07-19 | — | — | WO | claimed |
| US-5543316-A | INCLUDING A SUGAR, A SERUM ALBUMIN, A CALCIUM SALT, A PHOSPHATE SALT, A SOURCE OF IRON, AMINO ACIDS, VITAMINS, GROUP I SALT AND A GROUP II SALT | DIACRIN, INC. (US) | 1996-08-06 | — | — | US | claimed |
| EP-0488078-B1 | Diet free of phenylalanin for juveniles and adults affected with phenylketonurea | MILUPA AG (DE) | 1996-02-07 | — | — | EP | claimed |
| WO-1995029230-A1 | CULTURE MEDIUM FOR MAINTAINING VIABILITY OF MAMMALIAN CELLS | DIACRIN, INC. (US) | 1995-11-02 | — | — | WO | claimed |
| CN-1091952-A | Cosmetic composition | UNILEVER NV (NL) | 1994-09-14 | — | — | CN | claimed |
| EP-0189941-B1 | ANTIBIOTIC COMPOSITIONS | Bristol-Myers Squibb Company (US) | 1990-09-26 | — | — | EP | claimed |
| EP-0140027-B1 | AQUEOUS SOLUTION FOR COOLING COLD-ROLLED STEEL STRIP IN A CONTINUOUS ANNEALING PROCESS | NIPPON STEEL CORPORATION (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-0189941-A2 | Antibiotic compositions | Bristol-Myers Squibb Company (US) | 1986-08-06 | — | — | EP | claimed |
| EP-0150053-A2 | Hypocaloric low osmotic aqueous preparation for infusion | Oehmke, Martin, Dr. (DE) | 1985-07-31 | — | — | EP | claimed |