Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787144 | 1.00 | MAPT (0.50) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL3942968 | 0.82 | LRRK2 (0.47) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL1087950 | 0.78 | GAA (0.68) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL7440281 | 0.75 | MAPT (0.56) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL7440282 | 0.75 | MAPT (0.56) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL5710944 | 0.73 | GAA (0.43) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL5710948 | 0.73 | GAA (0.43) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL8874013 | 0.70 | GSK3B (0.56) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL8874017 | 0.70 | GSK3B (0.56) | MAPTGAAMAOAMAOBPDGFRA | |
| SCHEMBL6204410 | 0.69 | MAPT (0.48) | MAPTGAAMAOAMAOBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112258-A1 | SEROTONIN RECEPTOR AS A TARGET FOR THERAPY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2024-05-30 | — | — | WO | claimed |
| EP-3805210-B1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AUTOPHAGYSCIENCES INC (KR) | 2023-11-29 | — | — | EP | claimed |
| US-20220220106-A1 | QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2022-07-14 | — | — | US | claimed |
| CN-113767099-A | Quinoline compound, and medicinal composition and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-12-07 | — | — | CN | claimed |
| US-11168073-B2 | 3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2021-11-09 | — | — | US | claimed |
| EP-3288942-B1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-10-27 | — | — | EP | claimed |
| CN-107660205-B | Heterocyclic compounds as LSD1 inhibitors | 因赛特公司 | 2021-08-27 | — | — | CN | claimed |
| CN-113286794-A | KRAS mutein inhibitors | 北京加科思新药研发有限公司 | 2021-08-20 | — | — | CN | claimed |
| US-11084826-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | Janssen Sciences Ireland Unlimited Company (IE) | 2021-08-10 | — | — | US | claimed |
| EP-3805210-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Autophagysciences, Inc (KR) | 2021-04-14 | — | — | EP | claimed |
| WO-1995033721-A1 | 4-ARYL-1-(INDANMETHYL, DIHYDROBENZOFURANMETHYL OR DIHYDROBENZOTHIOPHENEMETHYL)PIPERIDINES, TETRAHYDROPYRIDINES OR PIPERAZINES | H. LUNDBECK A/S (DK) | 1995-12-14 | — | — | WO | claimed |
| EP-0221958-B1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Louis, William John (AU) | 1992-10-28 | — | — | EP | claimed |
| EP-0442878-A4 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | — | 1991-10-23 | — | — | EP | claimed |
| EP-0442878-A1 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-08-28 | — | — | EP | claimed |
| US-4977153-A | BETA ADRENOCEPTOR BLOCKING AGENTS | Louis, William J. (AU) | 1990-12-11 | — | — | US | claimed |
| WO-1989010355-A1 | DERIVATIVES OF TRYPTOPHAN AS CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1989-11-02 | — | — | WO | claimed |
| EP-0336356-A2 | Derivatives of tryptophan as CCK antagonists | ABBOTT LABORATORIES (US) | 1989-10-11 | — | — | EP | claimed |
| EP-0221958-A4 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LOUIS WILLIAM JOHN (AU) | 1987-11-25 | — | — | EP | claimed |
| EP-0221958-A1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LOUIS WILLIAM JOHN (AU) | 1987-05-20 | — | — | EP | claimed |
| WO-1986006717-A1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LOUIS WILLIAM JOHN (AU) | 1986-11-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168073-B2 | 3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same | VAPA, VAPB, SLC10A1 | MAPT 2179/4885GAA 441/4885MAOA 883/4885 |
| US-11084826-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | ZC3HAV1, MAVS, TYMP | MAPT 3325/4885GAA 2343/4885MAOA 2699/4885 |
| US-20220220106-A1 | QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | MTOR, RICTOR, EIF4E | MAPT 1257/4885GAA 811/4885MAOA 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.