SCHEMBL124178

SCHEMBL124178

Oc1ccc2c(c1)[nH]c1cc(O)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 4/20 0.57
HPGD P15428 3/20 0.57
GAA P10253 2/20 0.57
GLA P06280 1/20 0.57
GLI1 P08151 1/20 0.50
GLI2 P10070 1/20 0.50
SRC P12931 1/20 0.48
PRKACA P17612 1/20 0.48
PRKACG P22612 1/20 0.48
PRKACB P22694 1/20 0.48
PDPK1 O15530 1/20 0.47
HSP90AB1 P08238 1/20 0.47
CDK5 Q00535 1/20 0.46
CDK5R1 Q15078 1/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TDP1 Q9NUW8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365550 1.00 KDM4E (0.57) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL29561487 0.91 BCHE (0.58) KDM4EALDH1A1HPGDGAAGLA
Resorcinol SCHEMBL28074345 0.91 ALDH1A1 (0.55) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL28412384 0.91 BCHE (0.58) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL28022470 0.89 AHR (0.64) KDM4EALDH1A1GAAGLI1GLI2
SCHEMBL150279 0.89 AHR (0.64) KDM4EALDH1A1GAAGLI1GLI2
SCHEMBL30227209 0.89 AHR (0.64) KDM4EALDH1A1GAAGLI1GLI2
SCHEMBL11532887 0.87 PARP1 (0.53) KDM4EALDH1A1HPGDGAAGLA
Potassium SCHEMBL10868617 0.87 AHR (0.61) KDM4EALDH1A1GAAGLI1GLI2
SCHEMBL7251969 0.87 MEN1 (0.51) KDM4EALDH1A1HPGDGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2973 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820330-A Coumarin carbazole bipyridine salt type water-soluble two-photon initiator, and preparation method and application thereof 同济大学 2024-04-05 CN claimed
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
CN-113109960-A Horizontal alignment liquid crystal display element, liquid crystal composition, display device, and method for manufacturing horizontal alignment liquid crystal display element 捷恩智株式会社 2021-07-13 CN claimed
CN-112538358-A Horizontal alignment liquid crystal display element, liquid crystal composition, display device, and method for manufacturing horizontal alignment liquid crystal display element 捷恩智株式会社 2021-03-23 CN claimed
CN-112280566-A Liquid crystal element, liquid crystal composition, vehicle headlamp device, and method for manufacturing liquid crystal element 捷恩智株式会社 2021-01-29 CN claimed
CN-111679509-A Horizontal alignment liquid crystal display element, liquid crystal composition, display device, and method for manufacturing horizontal alignment liquid crystal display element 捷恩智株式会社 2020-09-18 CN claimed
CN-111454731-A Horizontal alignment liquid crystal display element, method for producing same, use of polymerizable compound, liquid crystal composition, and display device 捷恩智株式会社 2020-07-28 CN claimed
CN-111367123-A Horizontal alignment liquid crystal display element, liquid crystal composition, display device, and method for manufacturing horizontal alignment liquid crystal display element 捷恩智株式会社 2020-07-03 CN claimed
CN-110878215-A Horizontal alignment liquid crystal display element and method for producing same, liquid crystal composition, polymerizable compound and use thereof, and display device 捷恩智株式会社 2020-03-13 CN claimed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US claimed
WO-2002055585-A2 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2002-07-18 WO claimed
WO-2002055582-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
WO-2002055584-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
US-6395862-B1 CONTACTING DIARYLOXY COMPOUND WITH DIHYDRIC PHENOL IN THE PRESENCE OF ALKALI METAL TRIAZINE PYRIDYL SULFONATE, CARBOXY OR PHOSPHONATE GENERAL ELECTRIC COMPANY 2002-05-28 US claimed
US-6376640-B1 USING CESIUM POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2002-04-23 US claimed
US-6323304-B1 CONTACTING A DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF CATALYST COMPRISED OF ALKALI OR ALKALINE EARTH METAL-TRANSITION METAL FLUORIDE COMPOUND AND IN PRESENCE OF COCATALYST GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6323303-B1 POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6303737-B1 POLYCONDENSATION CATALYSTS WHICH ARE SALTS OF CERTAIN PHENANTHROLINE COMPOUNDS; EXCELLENT POLYMERIZATION RATES; REDUCING THE LEVEL OF BRANCHING SIDE REACTION, I.E., FORMATION OF FRIES PRODUCT GENERAL ELECTRIC COMPANY 2001-10-16 US claimed
US-6291631-B1 CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS GENERAL ELECTRIC COMPANY 2001-09-18 US claimed
US-5288836-A Low temperature interfacial polymerization; photreceptor materials XEROX CORPORATION (US) 1994-02-22 US claimed