Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12994233 | 0.84 | CHRM5 (0.32) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL13122987 | 0.84 | CHRM5 (0.32) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL12417871 | 0.83 | CHRM5 (0.34) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL17637745 | 0.80 | CHRM2 (0.30) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL23848862 | 0.79 | PYGB (0.35) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL13519745 | 0.78 | OGA (0.33) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL12417930 | 0.76 | CHRM5 (0.32) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL5161684 | 0.75 | — | — | |
| SCHEMBL13814326 | 0.75 | — | — | |
| SCHEMBL19500456 | 0.75 | CYP1A2 (0.34) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | CHRM5 4373/4885CHRM1 2987/4885CHRM3 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.