Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299858 | 0.85 | SMN1; SMN2 (0.51) | MAPTALDH1A1SMN1; SMN2FGFR1HPGD | |
| SCHEMBL2294183 | 0.84 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL19911407 | 0.74 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL12421824 | 0.74 | LCK (0.45) | MAPTALDH1A1FGFR1HSD17B10NPC1 | |
| SCHEMBL19848232 | 0.72 | FGFR1 (0.50) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL3346179 | 0.72 | ALDH1A1 (1.00) | MAPTALDH1A1SMN1; SMN2FGFR1NPC1 | |
| SCHEMBL2295162 | 0.72 | FGFR1 (0.42) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL166982 | 0.72 | QPCT (0.65) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL2295709 | 0.71 | TNF (0.40) | MAPTALDH1A1SMN1; SMN2FGFR1HSD17B10 | |
| SCHEMBL5952386 | 0.71 | FGFR1 (0.49) | MAPTALDH1A1SMN1; SMN2FGFR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003806-B2 | Integrin antagonists useful as anticancer agents | OSI Pharmaceuticals, LLC (US) | 2011-08-23 | — | — | US | disclosed |