Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959330 | 1.00 | PRKCA (0.56) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| Ether SCHEMBL9615811 | 0.93 | PRKCA (0.50) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL28489536 | 0.92 | PRKCA (0.61) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL10846866 | 0.92 | PRKCA (0.61) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL9330070 | 0.92 | PRKCA (0.61) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL15902853 | 0.92 | PRKCA (0.61) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL3469987 | 0.90 | PRKCA (0.59) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL29144896 | 0.90 | PRKCA (0.59) | PRKCAMAPTMAPK1PRKCDPRKCE | |
| SCHEMBL8669152 | 0.89 | PRKCA (0.47) | PRKCAMAPTMAPK1PRKCDGLS2 | |
| SCHEMBL22531093 | 0.87 | PRKCA (0.50) | PRKCAMAPTMAPK1PRKCDPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989602-B2 | having biological activity similar to PIM (acyl glycerol phosphatidylinositol manno-oligosacccharide) activity; asthma, allergic rhinitis, dermatitis, psoriasis, inflammatory bowel disease including Crohn's disease and ulcerative colitis, rheumatoid arthritis, multiple sclerosis, diabetes, systemic lupus | THE MALAGHAN INSTITUTE OF MEDICAL RESEARCH (NZ) | 2011-08-02 | — | — | US | disclosed |