Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508912 | 1.00 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL21147695 | 1.00 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL1726623 | 1.00 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL10457153 | 0.73 | CYP2C9 (0.42) | CYP2C9 | |
| SCHEMBL12765620 | 0.73 | — | — | |
| SCHEMBL8781694 | 0.71 | — | — | |
| SCHEMBL13742599 | 0.69 | — | — | |
| SCHEMBL31167963 | 0.69 | — | — | |
| SCHEMBL4064503 | 0.69 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL871897 | 0.69 | CYP2C9 (0.38) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-05-11 | — | — | US | disclosed |
| US-9890192-B2 | Targeted nitroxide agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2018-02-13 | — | — | US | disclosed |
| US-20160137692-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137692-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-05-19 | — | — | US | disclosed |
| US-9216976-B2 | Targeted nitroxide agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2015-12-22 | — | — | US | disclosed |
| US-9216976-B2 | Targeted nitroxide agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2015-12-22 | — | — | US | disclosed |
| US-20140378444-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140378444-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-12-25 | — | — | US | disclosed |
| US-8822541-B2 | Use of targeted nitroxide agents in mitigating or treating radiation injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822541-B2 | Use of targeted nitroxide agents in mitigating or treating radiation injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130102626-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2013-04-25 | — | — | US | disclosed |
| US-20130102626-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2013-04-25 | — | — | US | disclosed |
| US-8288551-B2 | Targeted nitroxide agents | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-10-16 | — | — | US | disclosed |
| US-20110172214-A1 | USE OF TARGETED NITROXIDE AGENTS IN PREVENTING, MITIGATING AND TREATING RADIATION INJURY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2011-07-14 | — | — | US | disclosed |
| US-20100035869-A1 | TARGETED NITROXIDE AGENTS | PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, UNIVERSITY OF | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172214-A1 | USE OF TARGETED NITROXIDE AGENTS IN PREVENTING, MITIGATING AND TREATING RADIATION INJURY | TXNRD2, TXN2, HSPE1 | CYP2C9 1157/4885 |
| US-20160137692-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CYP2C9 908/4885 |
| US-20100035869-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CYP2C9 908/4885 |
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CYP2C9 908/4885 |
| US-20140378444-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CYP2C9 908/4885 |
| US-20130102626-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | CYP2C9 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.