SCHEMBL124218

SCHEMBL124218

C1CC2CCOC2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19551074 1.00
SCHEMBL12906709 1.00
SCHEMBL11377504 1.00
SCHEMBL8173625 1.00
SCHEMBL19550911 1.00
SCHEMBL122714 1.00
SCHEMBL216077 0.94
SCHEMBL8666068 0.94
SCHEMBL873330 0.92 ALDH1A1 (0.37)
SCHEMBL16878743 0.92 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524978-B2 2-oxabicyclo[3.3.0]octane compounds, process for producing the same, optical resolver, method of separating diastereomer mixture, and method of optically resolving alcohol ZEON CORPORATION (JP) 2009-04-28 US claimed
CN-101264076-A Antifatigue agent SUNTORY LTD (JP) 2008-09-17 CN claimed
US-20060205960-A1 2-Oxabicyclo[3.3.0]octane compounds, process for producing the same, optical resolver, method of separating diastereomer mixture, and method of optically resolving alcohol ZEON CORPORATION (JP) 2006-09-14 US claimed
EP-1535917-A1 2-OXABICYCLO 3.3.0 OCTANE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, OPTICAL RESOLVER, METHOD OF SEPARATING DIASTEREOMER MIXTURE, AND METHOD OF OPTICALLY RESOLVING ALCOHOL Zeon Corporation (JP) 2005-06-01 EP claimed
US-4430497-A PRESENCE OF LEWIS ACID GRUENENTHAL GMBH (DE) 1984-02-07 US claimed
US-20240208932-A1 ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
US-20240208932-A1 ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
EP-4389742-A1 BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-06-26 EP disclosed
WO-2023091554-A9 NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS ICAGEN, LLC (US) 2024-05-23 WO disclosed
US-20240067633-A1 KETOHEXOKINASE INHIBITOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-02-29 US disclosed
US-20240067633-A1 KETOHEXOKINASE INHIBITOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-02-29 US disclosed
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF XIZANG HAISCO PHARMACEUTICALS CO., LTD. (CN) 2023-11-09 US disclosed
US-4430497-A PRESENCE OF LEWIS ACID GRUENENTHAL GMBH (DE) 1984-02-07 US disclosed
US-4379164-A Vasodilative 4-thia-PGI1 and 4-sulfinyl-PGI1 and derivatives thereof CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1983-04-05 US disclosed
EP-0059307-A1 Preparation of 2-oxa-bicyclo(3.3.0)octane compounds and their derivatives Grünenthal GmbH (DE) 1982-09-08 EP disclosed
US-4307112-A 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation FARMITALIA CARLO ERBA S.P.A. (IT) 1981-12-22 US disclosed
US-4250099-A ODORS; FLAVORS; RING EXPANSION OF A 1-OXYALKYL- OR 1-HYDROXYALKYL-2-OXA(4.1.0)BICYCLOHEPTANE GIVAUDAN CORPORATION (US) 1981-02-10 US disclosed
US-4246280-A ANTIASTHMATIC YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1981-01-20 US disclosed
US-4055589-A PROSTAGLANDINS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1977-10-25 US disclosed
US-3950362-A OXABICYCLOOCTANES AND PROCESS FOR THEIR MANUFACTURE CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed