Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186665 | 0.92 | ALDH1A1 (0.52) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL7035012 | 0.86 | CYP3A4 (0.48) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL7189766 | 0.82 | NPC1 (0.47) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL31457279 | 0.82 | NPC1 (0.47) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL7189805 | 0.79 | NPC1 (0.45) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL10625343 | 0.78 | MAPT (0.55) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL1095966 | 0.78 | ALDH1A1 (0.50) | ALDH1A1POLBPDE10AMAPTGAA | |
| SCHEMBL99201 | 0.78 | ALDH1A1 (0.61) | ALDH1A1POLBPDE10AMAPTGAA | |
| SCHEMBL837484 | 0.78 | ALDH1A1 (0.50) | ALDH1A1POLBNPC1MITFLMNA | |
| SCHEMBL2855620 | 0.78 | MAPT (0.45) | ALDH1A1POLBNPC1MITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |