Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 12/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200151 | 0.96 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2198346 | 0.93 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2196352 | 0.90 | MAPK14 (0.55) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL12424162 | 0.88 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2199324 | 0.87 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2196202 | 0.87 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2196282 | 0.87 | MAPK13 (0.40) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2198441 | 0.87 | MAPK1 (0.40) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2197456 | 0.86 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2198452 | 0.85 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |