Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198452 | 0.96 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2199982 | 0.91 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2198346 | 0.91 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL12424062 | 0.88 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2197543 | 0.85 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2200151 | 0.85 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2199324 | 0.85 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2196202 | 0.85 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2198441 | 0.84 | MAPK1 (0.40) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2196282 | 0.84 | MAPK13 (0.40) | MAPK13MAPK12MAPK11MAPK14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |