Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196971 | 0.90 | PPARA (0.36) | AKR1C3AKR1C2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2196223 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAL3MBTL1PPARABRD4 | |
| SCHEMBL2200388 | 0.87 | KCNA5 (0.37) | SMN1; SMN2LMNAL3MBTL1PPARACYP3A4 | |
| SCHEMBL2195077 | 0.83 | PPARA (0.36) | AKR1C3AKR1C2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2198784 | 0.81 | KCNA5 (0.37) | SMN1; SMN2LMNAL3MBTL1PPARACYP3A4 | |
| SCHEMBL2199012 | 0.81 | NPC1 (0.39) | SMN1; SMN2LMNAL3MBTL1PPARABRD4 | |
| SCHEMBL2199157 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAL3MBTL1PPARABRD4 | |
| SCHEMBL2197749 | 0.78 | ATM (0.38) | AKR1C3AKR1C2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2195122 | 0.77 | PPARA (0.39) | SMN1; SMN2LMNAL3MBTL1PPARABRD4 | |
| SCHEMBL2198688 | 0.77 | TSHR (0.45) | SMN1; SMN2LMNAL3MBTL1PPARABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | AKR1C3 393/4885AKR1C2 682/4885SMN1; SMN2 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.