Sugi Predict
/ Targets
/ CYP3A7
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to CYP3A7 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Physiological Study of the Human CYP3A Activity (PiSA) |
PHASE4 | COMPLETED |
| Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies |
PHASE4 | RECRUITING |
| Utilising Genotype Informed Bayesian Dosing of Tacrolimus in Children Post Solid Organ Transplantation. |
PHASE4 | RECRUITING |
| Cholestatic Drug-induced Liver Injury |
PHASE4 | UNKNOWN |
| Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma |
PHASE2 | NOT_YET_RECRUITING |
| RBN-2397 in Combination With Pembrolizumab in Patients With SCCL |
PHASE1/PHASE2 | UNKNOWN |
| Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer |
PHASE1/PHASE2 | COMPLETED |
| Oral Cannabidiol for Opioid Withdrawal |
PHASE1/PHASE2 | COMPLETED |
| 3 Month PHI PAD PoM Study |
PHASE2 | COMPLETED |
| Neoadjuvant Treatment of gBRCA-Mutated HER2-Negative Breast Cancer With HRS-1167 and Famitinib ± Camrelizumab |
PHASE2 | RECRUITING |
| Repeat Dose Safety and Efficacy Study for Compound to Treat Anemia |
PHASE2 | COMPLETED |
| A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| A Study of MRG002 in the Treatment of Patients With HER2-mutated Unresectable/Metastatic Non-small Cell Lung Cancer (NSCLC). |
PHASE2 | UNKNOWN |
| Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors |
PHASE1/PHASE2 | RECRUITING |
| A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer |
PHASE2 | COMPLETED |
| A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease Patients |
PHASE2 | RECRUITING |
| A Safety Study of EPC2407, A Anti-Cancer Drug With Vascular Disrupting Activity: In Patients With Advanced Cancer |
PHASE1 | COMPLETED |
| A Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060 |
PHASE1 | COMPLETED |
| A Phase I First-in-Human Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of SWA1211 Tablets in Subjects With Advanced Solid Tumors |
PHASE1 | RECRUITING |
| A Study of the Interaction of Other Drugs With TAK-279 in Healthy Adults |
PHASE1 | COMPLETED |
| Drug-Drug Interaction Study of Itraconazole With GST-HG171/Ritonavir in Healthy Participants |
PHASE1 | COMPLETED |
| Effect of Dexamethasone on CYP Enzyme Activity in Healthy Male Subjects |
PHASE1 | NOT_YET_RECRUITING |
| The Influence of Phenotype, Grapefruit Juice and Orange Juice on the Pharmacokinetics of Sunitinib in Cancer Patients |
PHASE1 | COMPLETED |
| A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer |
PHASE1 | RECRUITING |
| Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of AFQ056 in Children With Fragile X Syndrome (FXS) |
PHASE1 | COMPLETED |
| Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac |
EARLY_PHASE1 | RECRUITING |
| Influence of a Combined Pharmacogenetic Score on Through Plasma Voriconazole Concentrations in Haematological Patients |
nan | COMPLETED |
| PhaRmacOgenetics and Therapeutic Drug Monitoring In SchizophrEnia |
nan | NOT_YET_RECRUITING |
| Prospective Cytochrome P450 Genotyping and Clinical Outcomes in Patients With Psychosis |
nan | COMPLETED |
| Optimisation of Nutrition and Medication for Acutely Admitted Older Medical Patients |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a CYP3A7 binder may also engage these)