Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425960 | 1.00 | DRD2 (0.36) | DRD2OPRM1DRD4DRD3 | |
| SCHEMBL12385881 | 0.85 | DRD2 (0.37) | DRD2OPRM1DRD4DRD3 | |
| SCHEMBL15014565 | 0.85 | DRD2 (0.37) | DRD2OPRM1DRD4DRD3 | |
| SCHEMBL12384746 | 0.83 | DRD2 (0.36) | DRD2OPRM1DRD4DRD3 | |
| SCHEMBL12384706 | 0.83 | DRD2 (0.36) | DRD2OPRM1DRD4DRD3 | |
| SCHEMBL12424948 | 0.75 | DRD2 (0.36) | DRD2DRD3 | |
| SCHEMBL12424320 | 0.72 | TLR9 (0.38) | — | |
| SCHEMBL12561242 | 0.70 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL16508784 | 0.70 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL12424964 | 0.70 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201593-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201593-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | CCNY, CCNA1, CCNA2 | DRD2 3564/4885OPRM1 3594/4885DRD4 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.