Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125181 | 0.88 | PDCD1 (0.43) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10132731 | 0.79 | IDO1 (0.50) | ACACAFYNTSHRWHR1EGFR | |
| SCHEMBL19562010 | 0.78 | KCNA3 (0.43) | — | |
| SCHEMBL12125187 | 0.78 | SMARCA2 (0.39) | FYNCHEK1FGFR1CDK2KDR | |
| SCHEMBL426530 | 0.77 | IDO1 (0.47) | ACACAFYNTSHRWHR1KDM4E | |
| SCHEMBL1889602 | 0.75 | IDO1 (0.65) | BACE1ALOX5CDK4CCND1TSHR | |
| SCHEMBL17764797 | 0.75 | BACE1 (0.64) | BACE1ALOX5KDM4EALDH1A1LMNA | |
| SCHEMBL12074249 | 0.74 | ACACA (0.46) | ACACATSHRWHR1KDM4EALDH1A1 | |
| SCHEMBL13283973 | 0.74 | PDE10A (0.43) | ACACACDK4CCND1EGFRKDM4E | |
| SCHEMBL14903926 | 0.74 | ACACA (0.43) | ACACATSHRWHR1EGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7978391-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7847998-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-7582749-B2 | Photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7579022-B2 | Thermally reversible; absorption ratio greater than 2.3 | TRANSITIONS OPTICAL, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7560124-B2 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | TRANSITIONS OPTICAL, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| US-7557206-B2 | Thermally reversible; absorption ratio greater than 2.3; cell method | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7505189-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-7471436-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7466469-B2 | Polarizing, photochromic devices and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7457025-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070075388-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-04-05 | — | — | US | disclosed |
| US-20070053047-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053049-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053050-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070053048-A1 | Polirizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20070047055-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070047054-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070047053-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-01 | — | — | US | disclosed |
| US-20070041071-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-02-22 | — | — | US | disclosed |
| US-20070041073-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-02-22 | — | — | US | disclosed |