SCHEMBL1242589

SCHEMBL1242589

C=CCCCN(CC)CC=C

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
KCNH2 Q12809 7/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8417604 0.88 TSHR (0.50) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL8846761 0.86 MEN1 (0.40) TSHRALDH1A1MEN1POLBKMT2A
Hydrochloric Acid SCHEMBL22771826 0.86 TSHR (0.48) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL15787852 0.84 KCNH2 (0.43) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL27095806 0.83 MEN1 (0.44) TSHRMEN1POLBKMT2ATDP1
SCHEMBL22157599 0.82 TSHR (0.50) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL19596230 0.82 KCNH2 (0.45) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL22157402 0.82 TSHR (0.56) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL3116198 0.81 TSHR (0.50) TSHRALDH1A1MEN1POLBKMT2A
SCHEMBL22157450 0.80 TSHR (0.56) TSHRALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489264-A1 CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2019-05-29 EP disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
CN-1696235-B Barrier polishing solution CMP ROHM AND HAAS ELECTRONIC MATERIAL HOLDINGS INC 2014-04-09 CN disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
EP-2166074-B1 CLEANING AGENT ESPO CHEMICALS CORP (JP) 2013-03-20 EP disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
EP-2459598-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies LLC (US) 2012-06-06 EP disclosed
CN-1609156-B Composition for polishing semiconductor layers ROHM & HAAS ELECT MAT 2012-03-28 CN disclosed
US-7956026-B2 Cleaning agent ESPO CHEMICALS CORP. (JP) 2011-06-07 US disclosed
WO-2011016991-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed
US-20100216686-A1 CLEANING AGENT ESPO CHEMICALS CORPORATION (JP) 2010-08-26 US disclosed
EP-2166074-A1 CLEANING AGENT Espo Chemicals, Corp. (JP) 2010-03-24 EP disclosed
CN-100462415-C High-rate barrier polishing composition CMP ROHM AND HAAS ELECTRONIC M (US) 2009-02-18 CN disclosed
CN-1696235-A Barrier polishing solution CMP ROHM AND HAAS ELECTRONIC M (US) 2005-11-16 CN disclosed
CN-1616574-A High-rate barrier polishing composition CMP ROHM AND HAAS ELECTRONIC M (US) 2005-05-18 CN disclosed
CN-1609156-A Composition for polishing semiconductor layers ROHM & HAAS ELECT MAT (US) 2005-04-27 CN disclosed
EP-0874028-B1 INK COMPOSITION CONTAINING CATIONIC WATER-SOLUBLE RESIN SEIKO EPSON CORP (JP) 2003-06-11 EP disclosed
EP-0874028-A1 INK COMPOSITION CONTAINING CATIONIC WATER-SOLUBLE RESIN SEIKO EPSON CORPORATION (JP) 1998-10-28 EP disclosed
US-4909986-A Blend with water soluble polyner DAINIPPON INK (JP) 1990-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 TSHR 4812/4885ALDH1A1 3614/4885MEN1 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.