MSN — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL26098723	0.67	3/20
SCHEMBL31492743	0.67	3/20
SCHEMBL2808722	1.00	2/20
SCHEMBL29415450	1.00	2/20
SCHEMBL16706084	0.81	2/20
SCHEMBL29954899	0.81	2/20
SCHEMBL2116528	0.73	2/20
SCHEMBL3610631	0.73	2/20
SCHEMBL13186581	0.73	2/20
SCHEMBL16706087	0.73	2/20
SCHEMBL15033517	0.71	2/20
SCHEMBL13856681	0.69	2/20
SCHEMBL13725129	0.65	2/20
SCHEMBL13856221	0.64	2/20
SCHEMBL14542508	0.61	2/20
SCHEMBL13725224	0.58	2/20
SCHEMBL13856206	0.58	2/20
SCHEMBL13726135	0.57	2/20
SCHEMBL12768063	0.55	2/20
SCHEMBL16872914	0.54	2/20

Clinical trials — most relevant to MSN by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK)	PHASE2/PHASE3	RECRUITING
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Nerve Growth Factor Encapsulated With 2-methacryloyloxyethyl Phosphorylcholine Nanocapsules in the Treatment of Amyotrophic Lateral Sclerosis	PHASE2/PHASE3	NOT_YET_RECRUITING
Hormone Therapy With or Without Definitive Radiotherapy in Metastatic Prostate Cancer	PHASE2	UNKNOWN
A Multicenter Study of NAP (AL-108) in Schizophrenia	PHASE2	COMPLETED
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer	PHASE2	COMPLETED
A Clinical Study of Alanyl-Glutamine for Reduction of Post-Myomectomy Adhesions	PHASE1/PHASE2	COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome	PHASE1	COMPLETED
Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)	PHASE1	COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel	PHASE1	COMPLETED
Studying the Role of Circulating Tumor Cell Clusters in Patients With High-risk Early Breast Cancer, Study GALIA	nan	RECRUITING
The Roles of Neutrophil Elastase in Lung Cancer	nan	UNKNOWN
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression	nan	COMPLETED
Immune Cell Response to Stimuli	nan	RECRUITING
The Role of Maspin in Colorectal Carcinoma, an Immunohistochemical Study	nan	NOT_YET_RECRUITING
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events	nan	COMPLETED
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
The Activation of Hippo Pathway in Nasal Polyps	nan	UNKNOWN
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins.	nan	UNKNOWN
Analysis of Brain Metastasis in Patients With Breast Cancer, With and Without Over-Expression of HER-2	nan	COMPLETED
Safety and Efficacy of Combination Acthar Gel and Tacrolimus in the Treatment of Steroid Resistant Nephrotic Syndrome	nan	SUSPENDED
Influence of EMT on CTCs and Disease Progression in Prostate Cancer	nan	COMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion	nan	COMPLETED
Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis	nan	COMPLETED
Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial	nan	UNKNOWN
Thrombin Regulated Platelet Activation	nan	COMPLETED
Methylene Blue Intra-vital Nerve Staining	nan	UNKNOWN
Identification of Biomarkers for Early Detection of Pancreatic Cancer	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MSN binder may also engage these)

Protein	Name	Similarity
P26042	—	1.000	P26042 →
P26041	—	1.000	P26041 →
Q2HJ49	—	1.000	Q2HJ49 →
O35763	—	1.000	O35763 →
P26043	—	1.000	P26043 →
P26044	—	1.000	P26044 →
Q7PS12	—	1.000	Q7PS12 →
P52962	—	1.000	P52962 →
P31976	—	1.000	P31976 →
Q32LP2	—	1.000	Q32LP2 →
RDX	Radixin	1.000	landscape →
P31977	—	1.000	P31977 →
Q66I42	—	1.000	Q66I42 →
P46150	—	1.000	P46150 →
P26040	—	1.000	P26040 →
EZR	Ezrin	1.000	landscape →
Q9PU45	—	1.000	Q9PU45 →
P46662	—	0.999	P46662 →
Q8HZQ5	—	0.999	Q8HZQ5 →
Q63648	—	0.997	Q63648 →
Q170J7	—	0.996	Q170J7 →
Q29GR8	—	0.996	Q29GR8 →
B0WYY2	—	0.994	B0WYY2 →
P59750	—	0.993	P59750 →
P35240	—	0.993	P35240 →
Q24564	—	0.990	Q24564 →
Q6A028	—	0.989	Q6A028 →
Q7SYB5	—	0.986	Q7SYB5 →
Q86T65	—	0.983	Q86T65 →
Q5F4B2	—	0.983	Q5F4B2 →