SCHEMBL1242601

SCHEMBL1242601

C=CCCCC[Si](C)(CCCCC=C)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.34
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1243010 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1241819 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1241876 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1241846 0.98 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1242578 0.93 TSHR (0.39) TSHRALDH1A1LMNA
SCHEMBL1241842 0.84 TSHR (0.33) TSHRALDH1A1
SCHEMBL23499896 0.83 TSHR (0.39) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL824080 0.83 TSHR (0.39) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL247533 0.83 TSHR (0.39) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1398303 0.81 TSHR (0.43) TSHRALDH1A1LMNALPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924240-B1 Organopolysiloxane emulsions DOW CORNING (US) 2004-09-22 EP claimed
EP-0924240-A1 Organopolysiloxane emulsions DOW CORNING CORPORATION (US) 1999-06-23 EP claimed
EP-0661330-B1 Silicon resins and methods for their preparation DOW CORNING (US) 1998-04-08 EP claimed
EP-0718344-A1 Curable silicone coatings containing silicone resins DOW CORNING CORPORATION (US) 1996-06-26 EP claimed
US-5486578-A FORMING LAMINATES OF SILICONES WITH PLATINUM METAL CATALYSTS AND QUENCHING AGENTS THEN STRIPPING DOW CORNING CORPORATION (US) 1996-01-23 US claimed
EP-0661330-A1 Silicon resins and methods for their preparation DOW CORNING CORPORATION (US) 1995-07-05 EP claimed
US-5391673-A Silicon resins and methods for their preparation DOW CORNING CORPORATION (US) 1995-02-21 US claimed
CN-119684341-A Double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2025-03-25 CN disclosed
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-5486578-A FORMING LAMINATES OF SILICONES WITH PLATINUM METAL CATALYSTS AND QUENCHING AGENTS THEN STRIPPING DOW CORNING CORPORATION (US) 1996-01-23 US disclosed
EP-0661330-A1 Silicon resins and methods for their preparation DOW CORNING CORPORATION (US) 1995-07-05 EP disclosed
US-5391673-A Silicon resins and methods for their preparation DOW CORNING CORPORATION (US) 1995-02-21 US disclosed
EP-0361477-B1 Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE CO (JP) 1994-07-27 EP disclosed
EP-0535687-A1 Preparation process of silicone resin WACKER-CHEMIE GMBH (DE) 1993-04-07 EP disclosed
US-4980439-A Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE COMPANY LIMITED (JP) 1990-12-25 US disclosed
EP-0361477-A2 Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE COMPANY, LIMITED (JP) 1990-04-04 EP disclosed