Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242601 | 0.83 | TSHR (0.39) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL247533 | 0.83 | TSHR (0.39) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL23499896 | 0.83 | TSHR (0.39) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1398289 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1241846 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1243010 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1398303 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1241876 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL1241819 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 | |
| SCHEMBL26193033 | 0.81 | TSHR (0.43) | TSHRALDH1A1LMNALPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143362-B2 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100331444-A1 | COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF | 3M ESPE AG (A WHOLLY-OWNED SUBSIDUARY OF 3M COMPANY) | 2010-12-30 | — | — | US | disclosed |
| US-7807730-B2 | Composition containing unsaturated silicone compounds, dental materials containing them and use thereof | 3M ESPE AG (DE) | 2010-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331444-A1 | COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF | SMCHD1, CAD, ESD | TSHR 3257/4885ALDH1A1 1550/4885LMNA 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.