SCHEMBL12426123

SCHEMBL12426123

OC[C@H]1O[C@@H](c2cc(Cc3cccs3)ccc2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 19/20 0.66
▸ SLC5A1 P13866 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13218558 0.90 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL12426114 0.83 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL17480498 0.83 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL12426208 0.83 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL12662684 0.83 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL17480519 0.81 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL1853238 0.80 SLC5A2 (1.00) SLC5A2SLC5A1
Ym-543 Free Acid SCHEMBL14339156 0.80 SLC5A2 (1.00) SLC5A2SLC5A1
Ym-543 Free Acid SCHEMBL17034637 0.80 SLC5A2 (1.00) SLC5A2SLC5A1
Ym-543 Free Acid SCHEMBL10046215 0.80 SLC5A2 (1.00) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977466-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2011-07-12 — — US disclosed
US-7772407-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2010-08-10 — — US disclosed
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF ASTELLAS PHARMA INC. (JP) 2009-03-12 — — US disclosed
US-20070161787-A1 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-07-12 — — US disclosed
US-7202350-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-04-10 — — US disclosed
US-7202350-B2 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-04-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161787-A1 C-glycoside derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885SLC5A1 1/4885
US-20090069252-A1 C-GLYCOSIDE DERIVATIVES AND SALTS THEREOF SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885SLC5A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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