Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427579 | 0.91 | PRKCA (0.50) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL804075 | 0.91 | PRKCA (0.53) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL804300 | 0.89 | PRKCA (0.59) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL12427909 | 0.88 | PRKCA (0.58) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL12427728 | 0.88 | PRKCA (0.58) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL10283729 | 0.86 | PRKCA (0.53) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL3571241 | 0.85 | PRKCA (0.59) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL804152 | 0.84 | PRKCA (0.48) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL12427928 | 0.84 | PRKCA (0.59) | PRKCAMMP12NR1I2SCN9ACCKBR | |
| SCHEMBL12427618 | 0.84 | PRKCA (0.49) | PRKCAMMP12NR1I2SCN9ACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |