SCHEMBL12428429

SCHEMBL12428429

O=C(O)c1cc(C2=NN(c3ccccc3)C(=O)/C2=C\c2ccc(-c3ccc4c(c3)CCCN4c3ccccc3)s2)ccc1O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 6/20 0.43
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
RECQL P46063 1/20 0.41
GALK1 P51570 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
THRB P10828 1/20 0.38
KAT8 Q9H7Z6 1/20 0.37
EP300 Q09472 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428436 0.92 MEN1 (0.48) PTPN22KDM4EMEN1ALDH1A1GAA
SCHEMBL12428432 0.90 KAT8 (0.45) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL14289169 0.83 KDM4E (0.38) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL12428430 0.83 SCN9A (0.42) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL12428249 0.82 EP300 (0.41) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL12428451 0.81 SCN9A (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL12428264 0.81 EP300 (0.40) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL12428261 0.81 EP300 (0.40) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL12428433 0.78 MAPT (0.39) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL12428435 0.77 KMT2A (0.36) KDM4EMEN1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977570-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
US-20090084441-A1 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-04-02 US disclosed
EP-1885015-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2008-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090084441-A1 Dye-sensitized photoelectric conversion device CRY1, H1-5, H1-0 PTPN22 2066/4885KDM4E 314/4885MEN1 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.