Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
| ▸ | GLP1R | P43220 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12428482 | 1.00 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12428078 | 1.00 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12429244 | 0.94 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12428040 | 0.94 | PRKCA (0.41) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12428449 | 0.93 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL10283283 | 0.92 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL803712 | 0.92 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12428079 | 0.92 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL12427977 | 0.92 | PRKCA (0.41) | PRKCAMMP12SCN9ANR1I2CYP3A4 | |
| SCHEMBL10283285 | 0.92 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |