Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 6/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12429609 | 0.87 | FEN1 (0.34) | FEN1ALOX5AP | |
| SCHEMBL12428877 | 0.81 | FEN1 (0.35) | FEN1ALOX5AP | |
| SCHEMBL12428785 | 0.81 | NPC1 (0.32) | — | |
| SCHEMBL12429712 | 0.80 | FEN1 (0.38) | FEN1ALOX5AP | |
| SCHEMBL12429730 | 0.76 | — | — | |
| SCHEMBL15834804 | 0.75 | ALDH1A1 (0.44) | FEN1ALOX5APKIF11CYP3A4 | |
| SCHEMBL12428174 | 0.75 | HDAC1 (0.32) | — | |
| SCHEMBL24122283 | 0.73 | RARB (0.36) | CYP17A1CYP11B1CYP11B2KIF11RARB | |
| SCHEMBL13000447 | 0.73 | HTR2C (0.32) | FEN1ALOX5AP | |
| SCHEMBL18354770 | 0.72 | PTGES2 (0.42) | CYP17A1CYP11B1CYP11B2KIF11RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351741-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING NITROGEN-CONTAINING HETEROCYCLIC RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |