Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 8/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12429550 | 0.87 | FEN1 (0.37) | FEN1ALOX5APHDAC4 | |
| SCHEMBL12429609 | 0.78 | FEN1 (0.34) | FEN1ALOX5AP | |
| SCHEMBL13439395 | 0.77 | ACACB (0.33) | HDAC4 | |
| SCHEMBL12428877 | 0.77 | FEN1 (0.35) | FEN1ALOX5AP | |
| SCHEMBL12429712 | 0.76 | FEN1 (0.38) | FEN1ALOX5AP | |
| SCHEMBL13310771 | 0.74 | HDAC4 (0.42) | HDAC1KDM1AHDAC6HDAC2HDAC11 | |
| SCHEMBL20370270 | 0.74 | AKR1C3 (0.36) | HDAC1KDM1AFEN1ALOX5AP | |
| SCHEMBL14234530 | 0.74 | AKR1C3 (0.37) | HDAC1KDM1AHDAC6 | |
| SCHEMBL13901980 | 0.73 | FEN1 (0.41) | FEN1ALOX5APHDAC4 | |
| SCHEMBL15782786 | 0.73 | RAB9A (0.40) | FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351741-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING NITROGEN-CONTAINING HETEROCYCLIC RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |