Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL773040 | 0.99 | PRKCA (0.38) | PRKCAMMP12SCN9AHPGDMEN1 | |
| SCHEMBL804172 | 0.95 | PRKCA (0.39) | PRKCAMMP12SCN9AHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL772229 | 0.95 | PRKCA (0.39) | PRKCAMMP12SCN9AHPGDMEN1 | |
| SCHEMBL12428661 | 0.91 | SCN9A (0.34) | PRKCAMMP12SCN9AHPGDALDH1A1 | |
| SCHEMBL771979 | 0.90 | PRKCA (0.39) | PRKCAMMP12SCN9AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL774293 | 0.90 | SCN9A (0.34) | PRKCAMMP12SCN9AHPGDALDH1A1 | |
| SCHEMBL3785533 | 0.88 | PRKCA (0.39) | PRKCAMMP12SCN9AHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL773020 | 0.88 | PRKCA (0.39) | PRKCAMMP12SCN9AHPGDNPC1 | |
| SCHEMBL12427654 | 0.88 | SCN9A (0.34) | PRKCAMMP12SCN9AHPGDALDH1A1 | |
| SCHEMBL10283203 | 0.87 | PRKCA (0.38) | PRKCAMMP12SCN9AHPGDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |