Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL771911 | 0.99 | PRKCA (0.48) | PRKCAMMP12SCN9ANR1I2CASR | |
| SCHEMBL771459 | 0.97 | PRKCA (0.51) | PRKCAMMP12SCN9ANR1I2CASR | |
| Hydrochloric Acid SCHEMBL773592 | 0.96 | PRKCA (0.50) | PRKCAMMP12SCN9ANR1I2CASR | |
| Hydrochloric Acid SCHEMBL771881 | 0.96 | PRKCA (0.50) | PRKCAMMP12SCN9ANR1I2CASR | |
| SCHEMBL803733 | 0.93 | PRKCA (0.49) | PRKCAMMP12SCN9ANR1I2CASR | |
| Hydrochloric Acid SCHEMBL772835 | 0.92 | PRKCA (0.49) | PRKCAMMP12SCN9ANR1I2CYP2C9 | |
| SCHEMBL803866 | 0.92 | PRKCA (0.50) | PRKCAMMP12SCN9ANR1I2CASR | |
| SCHEMBL12429508 | 0.92 | PRKCA (0.50) | PRKCAMMP12SCN9ANR1I2CASR | |
| SCHEMBL12429072 | 0.92 | PRKCA (0.49) | PRKCAMMP12SCN9ANR1I2CASR | |
| SCHEMBL773492 | 0.92 | PRKCA (0.48) | PRKCAMMP12SCN9ANR1I2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |