SCHEMBL12430461

SCHEMBL12430461

O=C(CF)c1ccoc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988633 0.82 TRPA1 (0.69)
SCHEMBL7142769 0.78
SCHEMBL11849341 0.78
SCHEMBL6627157 0.78
SCHEMBL2379273 0.78
SCHEMBL4995985 0.77 TRPA1 (0.53)
Hydrochloric Acid SCHEMBL9372749 0.77 TRPA1 (0.53)
SCHEMBL5160772 0.75 CYP3A4 (0.54)
SCHEMBL826915 0.75 TRPA1 (0.66)
SCHEMBL5802096 0.75 CYP3A4 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1741693-B1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS NAGOYA IND SCIENCE RES INST (JP) 2011-08-03 EP disclosed
US-20070225528-A1 Process for Producing Optically Active Alcohol NAGOYA INDUSTRIAL SCIENCE RESEARCH CENTER (JP) 2007-09-27 US disclosed
EP-1741693-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS Nagoya Industrial Science Research Institute (JP) 2007-01-10 EP disclosed