SCHEMBL1243243

SCHEMBL1243243

C1CC2CNCCC2CN1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 1/20 0.47
KCNH2 Q12809 1/20 0.36
SLC6A1 P30531 4/20 0.35
SLC6A11 P48066 3/20 0.35
SLC6A13 Q9NSD5 3/20 0.35
GABRA5 P31644 3/20 0.35
GABRB2 P47870 3/20 0.35
SLC6A12 P48065 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRA4 P48169 2/20 0.35
GABRR1 P24046 1/20 0.35
PNMT P11086 1/20 0.34
CHRNB2 P17787 2/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA4 P43681 2/20 0.33
HTR3A P46098 1/20 0.32
HTR2C P28335 1/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007981 1.00 CCR5 (0.47) CCR5KCNH2SLC6A1SLC6A11SLC6A13
SCHEMBL13250365 1.00 CCR5 (0.47) CCR5KCNH2SLC6A1SLC6A11SLC6A13
SCHEMBL15601035 0.93
SCHEMBL2262923 0.93
SCHEMBL9938147 0.93
SCHEMBL5241187 0.93 CCR5 (0.41) CCR5KCNH2SLC6A1SLC6A11SLC6A13
SCHEMBL2262928 0.93
SCHEMBL1830086 0.93
SCHEMBL17006846 0.93
SCHEMBL474266 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 EP claimed
US-20250129078-A1 ERBB2 INHIBITORS COGENT BIOSCIENCES, INC. 2025-04-24 US claimed
WO-2024215809-A2 ERBB2 INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-10-17 WO claimed
EP-3660069-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2024-01-03 EP claimed
EP-3569630-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2022-08-03 EP claimed
EP-3569629-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2022-07-06 EP claimed
CN-111234182-A Fast curing epoxy system 赢创运营有限公司 2020-06-05 CN claimed
US-20200172723-A1 FAST-CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2020-06-04 US claimed
EP-3660069-A1 FAST CURING EPOXY SYSTEMS Evonik Operations GmbH (DE) 2020-06-03 EP claimed
CN-110498905-A Expediting setting type epoxy systems EVONIK DEGUSSA GMBH 2019-11-26 CN claimed
CN-110498904-A Expediting setting type epoxy systems EVONIK DEGUSSA GMBH 2019-11-26 CN claimed
US-20190352449-A1 FAST-CURING EPOXY SYSTEMS EVONIK DEGUSSA GMBH (DE) 2019-11-21 US claimed
US-20190352452-A1 FAST-CURING EPOXY SYSTEMS EVONIK DEGUSSA GMBH (DE) 2019-11-21 US claimed
EP-3569630-A1 FAST CURING EPOXY SYSTEMS Evonik Degussa GmbH (DE) 2019-11-20 EP claimed
EP-3569629-A1 FAST CURING EPOXY SYSTEMS Evonik Degussa GmbH (DE) 2019-11-20 EP claimed
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US disclosed
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 EP disclosed
US-20080004287-A1 Substituted Piperidines that Increase P53 Activity and the Uses Thereof SCHERING CORPORATION 2008-01-03 US disclosed
EP-1790639-A1 COMPOUND CONTAINING BASIC GROUP AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-30 EP disclosed
EP-1790639-A1 COMPOUND CONTAINING BASIC GROUP AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004287-A1 Substituted Piperidines that Increase P53 Activity and the Uses Thereof TP53, MDM2, TP53BP1 CCR5 3272/4885KCNH2 4299/4885SLC6A1 4849/4885
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF PTPN6, PTPN1, PTPN11 CCR5 725/4885KCNH2 4210/4885SLC6A1 1794/4885
US-20250129078-A1 ERBB2 INHIBITORS ERBB2, ERBB3, EGFR CCR5 1135/4885KCNH2 3531/4885SLC6A1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.