Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391382 | 0.93 | ACACB (0.50) | PPARDPPARANPC1RAB9AMEN1 | |
| SCHEMBL1391005 | 0.88 | ACACB (0.49) | PPARDPPARANPC1RAB9AMEN1 | |
| SCHEMBL12432312 | 0.87 | PPARD (0.47) | PPARDPPARAACACBACACA | |
| SCHEMBL1391059 | 0.84 | TP53 (0.53) | PPARDPPARANPC1ACACBACACA | |
| SCHEMBL1390605 | 0.83 | NPC1 (0.49) | PPARDPPARANPC1RAB9AMEN1 | |
| SCHEMBL1390525 | 0.82 | RAB9A (0.44) | NPC1RAB9AMEN1KMT2AACACB | |
| SCHEMBL1390974 | 0.81 | TP53 (0.52) | PPARDPPARANPC1ACACBACACA | |
| SCHEMBL1390754 | 0.79 | RAB9A (0.60) | PPARDPPARANPC1RAB9AMEN1 | |
| SCHEMBL12432316 | 0.77 | ACACB (0.42) | PPARDPPARANPC1RAB9AACACB | |
| SCHEMBL10239352 | 0.75 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351743-A1 | BICYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-08-03 | — | — | EP | disclosed |