SCHEMBL1243356

SCHEMBL1243356

C=CCCCCNC(C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.36
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11745768 0.98 TSHR (0.46) TSHRALDH1A1LMNAHRH4HRH3
SCHEMBL24672926 0.98 TSHR (0.46) TSHRALDH1A1LMNAHRH4HRH3
SCHEMBL31588184 0.98 TSHR (0.46) TSHRALDH1A1LMNAHRH4HRH3
SCHEMBL23696464 0.98 TSHR (0.46) TSHRALDH1A1LMNAHRH4HRH3
SCHEMBL4540412 0.93
SCHEMBL7565303 0.82
SCHEMBL2600364 0.79 HRH4 (0.43) ALDH1A1HRH4HRH3KDM4E
SCHEMBL23959466 0.77 TSHR (0.40) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL19233596 0.77 TSHR (0.35) TSHRALDH1A1LMNAABCC4MAPT
SCHEMBL7672129 0.76 TSHR (0.42) TSHRALDH1A1HRH4HRH3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4437009-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2024-10-02 EP claimed
EP-4437016-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2024-10-02 EP claimed
EP-4247866-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2023-09-27 EP claimed
WO-2023088853-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-25 WO claimed
WO-2023088855-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-25 WO claimed
WO-2022106689-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-27 WO claimed
EP-4437016-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2024-10-02 EP disclosed
EP-4437009-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2024-10-02 EP disclosed
CN-118234765-A Solution process for producing functionalized polyolefin SABIC环球技术有限责任公司 2024-06-21 CN disclosed
CN-118215688-A Solution process for producing functionalized polyolefin SABIC环球技术有限责任公司 2024-06-18 CN disclosed
CN-116368163-A Solution process for producing functionalized polyolefin SABIC环球技术有限责任公司 2023-06-30 CN disclosed
WO-2023088853-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-25 WO disclosed
WO-2023088855-A1 SOLUTION PROCESS FOR PRODUCTION OF FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-25 WO disclosed
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed
US-9579400-B2 Nanocarriers for drug delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-28 US disclosed
EP-2079479-B1 HCV NS3 PROTEASE INHIBITORS MERCK SHARP & DOHME (US) 2014-11-26 EP disclosed
EP-1913016-B1 MACROCYCLIC PEPTIDES AS HCV NS3 PROTEASE INHIBITORS MERCK SHARP & DOHME (US) 2013-01-16 EP disclosed
US-8278322-B2 HCV NS3 protease inhibitors MERCK SHARP & DOHME CORP. (US) 2012-10-02 US disclosed
US-20110028494-A1 HCV NS3 Protease Inhibitors MERCK SHARP & DOHME LLC 2011-02-03 US disclosed
WO-2008051475-A2 HCV NS3 PROTEASE INHIBITORS MERCK & CO., INC. (US) 2008-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028494-A1 HCV NS3 Protease Inhibitors HAVCR2, GTF3C3, CTSC TSHR 4610/4885ALDH1A1 1199/4885LMNA 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.