Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840007 | 0.83 | GRIA1 (0.32) | — | |
| SCHEMBL31588184 | 0.79 | TSHR (0.46) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL23696464 | 0.79 | TSHR (0.46) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL24672926 | 0.79 | TSHR (0.46) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL11745768 | 0.79 | TSHR (0.46) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL4744735 | 0.77 | HRH4 (0.37) | ALDH1A1 | |
| SCHEMBL3690414 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL1243356 | 0.77 | TSHR (0.42) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL27339585 | 0.77 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL14864944 | 0.75 | EPHX1 (0.42) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216828-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |