SCHEMBL12433773

SCHEMBL12433773

C=C=Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
CYP2D6 P10635 1/20 0.52
LMNA P02545 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 2/20 0.45
ALDH1A1 P00352 2/20 0.45
NT5E P21589 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
CA2 P00918 2/20 0.41
CA1 P00915 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
RPS6KA3 P51812 1/20 0.40
PHLPP2 Q6ZVD8 3/20 0.37
ATIC P31939 1/20 0.35
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
RAD1 O60671 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2278953 0.81 POLB (0.53) POLBCYP2D6LMNATDP1TSHR
SCHEMBL31315339 0.79 CA1 (0.66) POLBCYP2D6LMNATDP1TSHR
Fluoride SCHEMBL10885011 0.79 POLB (0.52) POLBCYP2D6LMNATDP1TSHR
SCHEMBL668791 0.79 CA1 (0.66) POLBCYP2D6LMNATDP1TSHR
SCHEMBL1194107 0.78 CA1 (0.63) POLBCYP2D6LMNATDP1TSHR
SCHEMBL22604030 0.76 CYP3A4 (0.36) TSHRCA2CA1P2RY6
Water SCHEMBL3903037 0.76 CA1 (0.61) POLBCYP2D6LMNATDP1TSHR
SCHEMBL14527054 0.76 POLB (0.57) POLBCYP2D6LMNATDP1TSHR
SCHEMBL18624977 0.75 POLB (0.83) POLBCYP2D6LMNATDP1TSHR
SCHEMBL28560987 0.75 POLB (0.83) POLBCYP2D6LMNATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2096145-B1 WATER-SOLUBLE AZO COMPOUNDS OR SALTS THEREOF, INK COMPOSITIONS AND COLORED PRODUCTS NIPPON KAYAKU KK (JP) 2011-08-03 EP disclosed