Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.83 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ATIC | P31939 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.49 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560987 | 1.00 | POLB (0.83) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL2171353 | 0.91 | LMNA (0.74) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL4808253 | 0.91 | LMNA (0.74) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL408153 | 0.91 | POLB (1.00) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL6563719 | 0.91 | POLB (1.00) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL9612273 | 0.89 | POLB (0.68) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL4489023 | 0.89 | LMNA (0.71) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL5752505 | 0.89 | TSHR (0.75) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL13154694 | 0.89 | POLB (0.68) | POLBCYP2D6RPS6KA3LMNAMEN1 | |
| SCHEMBL28788411 | 0.89 | POLB (0.96) | POLBCYP2D6RPS6KA3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995365-B2 | Compounds and systems for improving signal detection | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2021-05-04 | — | — | US | disclosed |
| EP-3350350-B1 | COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-10435741-B2 | Compounds and systems for improving signal detection | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| US-20190106742-A1 | COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2019-04-11 | — | — | US | disclosed |
| US-20170145494-A1 | COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-3141263-A1 | METAL-ORGANIC FRAMEWORK/STIMULUS-RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | National University Corporation Hokkaido University (JP) | 2017-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | ORAI1, SARAF, TRPM8 | POLB 4374/4885CYP2D6 4834/4885RPS6KA3 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.