Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202108 | 0.86 | PARP1 (0.51) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL202107 | 0.86 | PARP1 (0.51) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL201514 | 0.81 | FAAH (0.59) | PARP1FAAH | |
| SCHEMBL201462 | 0.81 | FAAH (0.59) | PARP1FAAH | |
| SCHEMBL201463 | 0.81 | FAAH (0.59) | PARP1FAAH | |
| SCHEMBL201942 | 0.80 | PARP1 (0.57) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL201941 | 0.80 | PARP1 (0.57) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL2562475 | 0.78 | PARP1 (0.57) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL27816266 | 0.78 | PARP1 (0.61) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL203644 | 0.77 | PARP1 (0.56) | PARP1TNKSPARP15PARP14PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |