Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.41 |
| ▸ | BHMT | Q93088 | 1/20 | 0.40 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984957 | 1.00 | SLC7A5 (0.46) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| SCHEMBL13026596 | 1.00 | SLC7A5 (0.46) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| SCHEMBL13176779 | 0.88 | GABRR1 (0.39) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| SCHEMBL16118377 | 0.88 | NOS2 (0.46) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL28213243 | 0.86 | SLC7A5 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| SCHEMBL16626924 | 0.86 | GABRR1 (0.46) | GABRR1ENPEP | |
| SCHEMBL11193240 | 0.86 | GABRR1 (0.46) | GABRR1ENPEP | |
| SCHEMBL6537085 | 0.86 | GABRR1 (0.46) | GABRR1ENPEP | |
| SCHEMBL5518553 | 0.86 | GABRR1 (0.46) | GABRR1ENPEP | |
| Cystine SCHEMBL8332353 | 0.86 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178287-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2011-07-21 | — | — | US | disclosed |
| US-20110178287-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2011-07-21 | — | — | US | disclosed |