Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 6/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876259 | 0.84 | CYP2A6 (0.64) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL14689056 | 0.80 | CYP2A6 (0.58) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL11937121 | 0.80 | CYP2A6 (0.50) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL1561225 | 0.80 | CYP2A6 (0.50) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL1560042 | 0.80 | CYP2A6 (0.50) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL28208215 | 0.78 | CYP2A6 (0.55) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL10834707 | 0.77 | CYP2A6 (0.51) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL29779710 | 0.77 | CYP2A6 (0.51) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL14689223 | 0.75 | CYP2A6 (0.53) | CYP2A6CYP3A4PIM1PIM3PIM2 | |
| SCHEMBL473704 | 0.74 | ADORA2A (0.45) | CYP2A6CYP3A4PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | disclosed |
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | AOC3, CBR3, IDH3B | CYP2A6 705/4885CYP3A4 743/4885PIM1 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.