Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561368 | 0.88 | POLB (0.36) | MAPK10PIM1GSK3BCYP2A6MEN1 | |
| SCHEMBL12435540 | 0.86 | CTPS1 (0.43) | — | |
| SCHEMBL12435522 | 0.82 | PIM1 (0.39) | PIM1CYP2A6GRIN1GRIN2BCYP2E1 | |
| SCHEMBL1560919 | 0.81 | CHEK1 (0.43) | PIM1 | |
| SCHEMBL11929456 | 0.79 | SLC2A1 (0.44) | PIM1CYP2A6CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL12435456 | 0.77 | CYP2A6 (0.43) | PIM1CYP2A6GRIN1GRIN2BCYP2E1 | |
| SCHEMBL12435461 | 0.76 | PIM1 (0.46) | PIM1CYP2A6GRIN1GRIN2BCYP2E1 | |
| SCHEMBL1560996 | 0.76 | CTPS1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL12435549 | 0.75 | PDPK1 (0.39) | PIM1CYP2A6CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL11929454 | 0.75 | CYP2A6 (0.43) | PIM1CYP2A6GRIN1GRIN2BCYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | AOC3, CBR3, IDH3B | MAPK10 2400/4885PIM1 2969/4885GSK3B 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.