⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651286 | 0.78 | — | — | |
| SCHEMBL467306 | 0.74 | — | — | |
| SCHEMBL1768412 | 0.74 | — | — | |
| SCHEMBL4729422 | 0.70 | — | — | |
| SCHEMBL3947126 | 0.69 | — | — | |
| SCHEMBL2454500 | 0.67 | — | — | |
| SCHEMBL2351201 | 0.67 | CALM1 (0.46) | — | |
| SCHEMBL18396913 | 0.66 | — | — | |
| SCHEMBL18396886 | 0.66 | — | — | |
| SCHEMBL1727698 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436903-A | Process for the production of 7 β-substituted-3-unsubstituted-3-cephem-4-carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | claimed |
| EP-0087274-A2 | Pyrimidone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-08-31 | — | — | EP | claimed |
| EP-0016725-B1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYCEPHAM COMPOUNDS | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | claimed |
| US-4301279-A | Process for the production of 3-hydroxy compounds | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | claimed |
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | claimed |
| EP-0016725-A1 | Process for the preparation of 3-hydroxycepham compounds | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | claimed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | claimed |
| EP-1797096-B1 | PYRAZOLOPYRIMIDINES AS INHIBITORS OF PROTEIN KINASE B (AKT) | BAYER SCHERING PHARMA AG (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-7879853-B2 | tyrosisne kinase inhibitors such as N-[4-(6-Dibenzofuran-4-yl-pyrimidin-4-ylamino)-phenyl]-4-morpholin-4-yl-benzamide, used as anticasrcinogenic or antoproliferative agents, especially in the treatment of breast cancer | BAYER SCHERING PHARMA AG (DE) | 2011-02-01 | — | — | US | disclosed |
| US-7745446-B2 | Pyrazolo[1,5-c]pyrimidines | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-29 | — | — | US | disclosed |
| EP-1763526-B1 | 4,6-DISUBSTITUTED PYRIMIDINES AND THEIR USE AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| US-20070254046-A1 | Novel Pyrazolopyrimidines | ALTANA PHARMA AG (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20070208034-A1 | 4,6-disubstituted pyrimidines and their use as protein kinase inhibitors | ATLANTA PHARMA AG (DE) | 2007-09-06 | — | — | US | disclosed |
| EP-0016725-B1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYCEPHAM COMPOUNDS | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | disclosed |
| US-4364865-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| EP-0055217-A2 | Process for the preparation of derivatives of 7-beta-substituted 3-cephem-4-carboxylic acids not substituted in position 3 | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | disclosed |
| US-4301279-A | Process for the production of 3-hydroxy compounds | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| EP-0016725-A1 | Process for the preparation of 3-hydroxycepham compounds | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | disclosed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |