Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 15/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060630 | 0.87 | GGPS1 (0.57) | GGPS1NPSR1L3MBTL1FDPSCYP2D6 | |
| SCHEMBL14199559 | 0.83 | GGPS1 (0.52) | GGPS1NPSR1L3MBTL1FDPSCYP2D6 | |
| SCHEMBL12060601 | 0.69 | GGPS1 (0.83) | GGPS1FDPS | |
| SCHEMBL12060604 | 0.67 | GGPS1 (0.58) | GGPS1NPSR1L3MBTL1FDPS | |
| SCHEMBL7509429 | 0.66 | KMT2A (0.67) | CYP2D6ALDH1A1 | |
| SCHEMBL14199553 | 0.65 | GGPS1 (0.75) | GGPS1FDPS | |
| Bromide SCHEMBL7048108 | 0.65 | KMT2A (0.69) | CYP2D6ALDH1A1 | |
| SCHEMBL12060627 | 0.65 | GGPS1 (0.56) | GGPS1FDPS | |
| SCHEMBL12060534 | 0.65 | GGPS1 (0.56) | GGPS1FDPS | |
| SCHEMBL12060613 | 0.65 | GGPS1 (0.83) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802641-B1 | BISPHOSPHONATE COMPOUNDS AND METHODS FOR BONE RESORPTION DISEASES, CANCER, BONE PAIN, IMMUNE DISORDERS, AND INFECTIOUS DISEASES | UNIV ILLINOIS (US) | 2011-08-10 | — | — | EP | disclosed |