Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 15/20 | 0.52 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060630 | 0.92 | GGPS1 (0.57) | GGPS1FDPSNPSR1L3MBTL1CYP2D6 | |
| SCHEMBL12435684 | 0.83 | GGPS1 (0.48) | GGPS1FDPSNPSR1L3MBTL1CYP2D6 | |
| SCHEMBL14199553 | 0.82 | GGPS1 (0.75) | GGPS1FDPS | |
| SCHEMBL14199572 | 0.80 | GGPS1 (0.53) | GGPS1FDPSNPSR1L3MBTL1 | |
| SCHEMBL14199557 | 0.78 | GGPS1 (0.74) | GGPS1FDPSKMT2A | |
| SCHEMBL14199582 | 0.78 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL14199556 | 0.78 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL14199570 | 0.78 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL12257842 | 0.77 | GGPS1 (0.57) | GGPS1FDPS | |
| SCHEMBL12060532 | 0.76 | GGPS1 (0.70) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |