SCHEMBL12435754

SCHEMBL12435754

c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4ccc(-c5ccc6ccccc6c5)nc4)c4ccccc34)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP11B1 P15538 5/20 0.41
CYP11B2 P19099 5/20 0.41
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP1A2 P05177 3/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
CTRC Q99895 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
AXL P30530 1/20 0.38
CDK8 P49336 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12436954 0.94 CYP1A1 (0.46) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL12436195 0.93 HSD17B1 (0.44) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL12436885 0.93 CYP1A1 (0.47) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL28223699 0.91 HSD17B1 (0.44) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL12436891 0.90 CYP1A1 (0.47) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL17680014 0.90 CYP11B1 (0.46) CYP1A1CYP1B1CYP11B1CYP11B2CYP1A2
SCHEMBL21249207 0.88 CYP11B1 (0.45) CYP1A1CYP1B1CYP11B1CYP11B2CYP1A2
SCHEMBL15977420 0.87 CYP1A1 (0.43) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL24686653 0.86 CYP11B1 (0.53) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A
SCHEMBL12436956 0.86 CYP1A1 (0.42) CYP1A1CYP1B1CYP11B1CYP11B2ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011037380-A9 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2011-08-04 WO disclosed
WO-2011037380-A2 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2011-03-31 WO disclosed