⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578515 | 0.88 | CA1 (0.30) | — | |
| SCHEMBL2885291 | 0.86 | CA12 (0.33) | — | |
| SCHEMBL81587 | 0.84 | — | — | |
| SCHEMBL1792330 | 0.84 | — | — | |
| SCHEMBL1492439 | 0.81 | DNM1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL9003263 | 0.81 | — | — | |
| SCHEMBL28471846 | 0.81 | — | — | |
| Water SCHEMBL11566326 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL2311158 | 0.81 | TP53 (0.31) | — | |
| Bromide SCHEMBL7803664 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524700-B2 | Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics | SANOFI (FR) | 2013-09-03 | — | — | US | disclosed |
| US-20120323003-A1 | TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS | SANOFI (FR) | 2012-12-20 | — | — | US | disclosed |
| US-8273733-B2 | Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics | SANOFI (FR) | 2012-09-25 | — | — | US | disclosed |
| EP-2477598-A2 | COSMETIC COMPOSITIONS CONTAINING THIOMERS FOR HAIR COLOR RETENTION | ELC Management LLC (US) | 2012-07-25 | — | — | EP | disclosed |
| US-20110229430-A1 | Cosmetic Compositions Containing Thiomers For Hair Color Retention | ELC MANAGEMENT LLC | 2011-09-22 | — | — | US | disclosed |
| WO-2011031706-A2 | COSMETIC COMPOSITIONS CONTAINING THIOMERS FOR HAIR COLOR RETENTION | ELC MANAGEMENT LLC (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20110028475-A1 | TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-02-03 | — | — | US | disclosed |
| US-7833999-B2 | Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics | SANOFI-AVENTIS (FR) | 2010-11-16 | — | — | US | disclosed |
| US-7670753-B2 | Lithographic printing plate precursor | EASTMAN KODAK COMPANY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080261146-A1 | Lithographic Printing Plate Precursor | EASTMAN KODAK COMPANY | 2008-10-23 | — | — | US | disclosed |
| EP-1782127-B1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK CO (US) | 2008-04-02 | — | — | EP | disclosed |
| US-20070105834-A1 | TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2007-05-10 | — | — | US | disclosed |
| EP-1782127-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK COMPANY (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006023667-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | EASTMAN KODAK COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |